README Title of Supplementary Material: Supplementary material associated with the manuscript Description: This material contains the supplementary files related to the results presented in the manuscript. Files included: * Table_S1.xlsx: supplementary results from the descriptive analysis. * Table_S2.xlsx: results from the additional statistical analysis. * Data_S1.csv: dataset used for the analyses. * Code_S1.R: script used for data processing and analysis. Data description: * ID: record identifier. * Age: age in years. * Group: study group. * Outcome: main variable analyzed. Required software: R version 4.4 or later and Microsoft Excel or compatible software. Notes: The data have been anonymized, and the file names correspond to the references used in the manuscript.