Health education interventions on knowledge and self-care practices for hypertensive disorders during pregnancy: systematic review and meta-analysis protocol



Palabras clave:

Health education, Knowledge, Self-care, Hypertension, Pregnancy-Induced, Systematic Review, Meta-Analysis



Hypertensive disorders of pregnancy are one of the leading complications of pregnancy and represent a critical threat to maternal and perinatal health worldwide.

Scientific evidence suggests that lack of knowledge and lack of preventive practices in pregnant women would be associated with an increased risk of hypertensive disorders of pregnancy.

The review of the existing literature is essential to recognize the impact of educational interventions aimed at improving the knowledge and self-care practices of pregnant women in the face of hypertensive disorders of pregnancy.

The findings of this study will provide strong scientific evidence for clinical practice, policies and programs in maternal perinatal health.

Introduction: Hypertensive disorders during pregnancy are a global health problem. Health education is a strategy that provides pregnant women with knowledge and skills for self-care. Objective: evaluate the effect of health education interventions on pregnant women's knowledge and self-care practices for hypertensive disorders in pregnancy, compared to standard prenatal care. Materials and Methods: Systematic review and meta-analysis protocol. The study record can be consulted in PROSPERO (CRD42021252401). The search will be conducted in the following databases, PubMed/MEDLINE, CENTRAL, LILACS, CINAHL, EMBASE, and WoS. Additionally, clinical trial records in ClinicalTrials and grey literatura in OpenGrey and Google Scholar. The search will include studies of health education intervention in knowledge and self-care practices about hypertensive disorders in pregnancy. All statistical analysis will be carried out with the Review Manager software. Data will be combined using random-effects models, binary data with odds ratios or relative risks, and continuous data using mean differences. Heterogeneity between studies will be assessed using the Q-Cochran test to measure the significance and the l2 statistic to measure magnitude. Discussion: This study will contribute to the knowledge of health interventions that are effective in guiding and educating pregnant women about the disease and self-care practices. Conclusion: The results of this study will be used to provide recommendations in the management of maternal perinatal care, that promote comprehensive care in accordance with the Primary Health Care policy.

How to cite this article: Ulloa-Sabogal Iliana Milena, Pérez-Jaimes Giovanny Andrés, Arias-Rojas Edier Mauricio, Cañon-Montañez Wilson. Health education interventions on knowledge and self-care practices for hypertensive disorders during pregnancy: systematic review and meta-analysis protocol. Revista Cuidarte. 2023;14(1):e2495.


Biografía del autor/a

Iliana Milena Ulloa-Sabogal, Universidad Industrial de Santander

RN, MSN. Faculty of Nursing, Universidad de Antioquia, Medellín, Colombia.

Giovanny Andrés Pérez-Jaimes, Universidad Industrial de Santander

RN. Nursing School, Universidad Industrial de Santander, Bucaramanga, Colombia.

Edier Mauricio Arias-Rojas, Universidad de Antioquia

RN, MSN, PhD. Faculty of Nursing, Universidad de Antioquia, Medellín, Colombia.

Wilson Cañon-Montañez, Universidad de Antioquia

RN, MSc. PhD. Faculty of Nursing, Universidad de Antioquia, Medellín, Colombia.


Mendoza MA, Moreno LC, Becerra CH, Díaz LA. Desenlaces materno-fetales de los embarazos con trastornos hipertensivos: Un estudio transversal. Rev. chil. obstet. ginecol. 2020; 85(1): 14-23.

Vial F, Baka NE, Herbain D. Preeclampsia. Eclampsia. EMC - Anestesia-Reanimación. 2020; 46(3): 1–19.

Umesawa M, Kobashi G. Epidemiology of hypertensive disorders in pregnancy: prevalence, risk factors, predictors and prognosis. Hypertens Res. 2016; 40(3): 213–220.

Mersha AG, Abegaz TM, Seid MA. Maternal and perinatal outcomes of hypertensive disorders of pregnancy in Ethiopia: systematic review and meta-analysis. BMC Pregnancy Childbirth. 2019; 19(1): 458–470.

Morales BG, Moya CT, Blanco NB, Moya NA, Moya AA, Moya RT. Trastornos hipertensivos durante el embarazo en gestantes del Policlínico Universitario "Santa Clara" (2015-2016). Rev Cuba Obstet y Ginecol. 2017; 43(2):1–14.

Hinkosa L, Temene A, Gebeyehu N. Risk factors associated with hypertensive disorders in pregnancy in Nekemte referral hospital, from July 2015 to June 2017, Ethiopia: case control study. BMC Pregnancy Childbirth. 2020; 20(1): 1–9.

Yiin YL, Pérez GR, López MT, Hidalgo LA, Chedraui PA. Resultados maternos y perinatales en gestantes con eclampsia. Rev Colomb Salud Libre. 2015;10(2):83–90.

Cruz IR, Merencio WB, Gutierrez GS, Ferreira NN, Almeida FA, Garcia JL. Maternal and fetal outcome in women with hypertensive disorders of pregnancy: the impact of prenatal care. Ther Adv Cardiovasc Dis. 2015; 9(4): 140–146.

Torres MA, Vega EG, Vinalay I, Cortaza L, Alfonso L. Factores de riesgo psicosociales asociados a preeclampsia en mujeres mexicanas: análisis comparado en tres Estados. Enferm Univ. 2018; 15(3): 226-243.

Frawley N, East C, Brennecke S. Women’s experiences of preeclampsia: a prospective survey of preeclamptic women at a single tertiary centre. J Obstet Gynaecol. 2020; 40(1): 65–69.

Hoedjes M, Berks D, Vogel I, Franx A, Bangma M, Darlington AS, et al. Postpartum depression after mild and severe preeclampsia. J Womens Health. 2011; 20(10): 1535–1542.

Chen L, Wang X, Ding Q, Shan N, Qi H. Development of postpartum depression in pregnant women with preeclampsia: a retrospective study. Biomed Res Int. 2019;1-7.

Roberts L, Davis GK, Homer CS. Depression, anxiety, and post-traumatic stress disorder following a hypertensive disorder of pregnancy: a narrative literature review. Front Cardiovasc Med. 2019;6: 1-14.

Stevens W, Shih T, Incerti D, Ton TG, Lee HC, Peneva D, et al. Short-term costs of preeclampsia to the United States health care system. Am J Obstet Gynecol. 2017; 217(3): 237-248.e16.

Hao J, Hassen D, Hao Q, Graham J, Paglia MJ, Brown J, et al. Maternal and infant health care costs related to preeclampsia. Obstet Gynecol. 2019; 134(6): 1227–1233. https://doi10.1097/AOG.0000000000003581

Kahsay HB, Gashe FE, Ayele WM. Risk factors for hypertensive disorders of pregnancy among mothers in Tigray region, Ethiopia: Matched case-control study. BMC Pregnancy Childbirth. 2018; 18(1): 1–10.

Salomon A, Ishaku S, Kirk KR, Warren CE. Detecting and managing hypertensive disorders in pregnancy: a cross-sectional analysis of the quality of antenatal care in Nigeria. BMC Health Serv Res. 2019; 19(1): 411–425.

Sheikh S, Qureshi RN, Khowaja AR, Salam R, Vidler M, Sawchuck D, et al. Health care provider knowledge and routine management of pre-eclampsia in Pakistan. Reprod Health. 2016; 13(2):107–113.

Fadare RI, Akpor OA, Oziegbe OB. knowledge and attitude of pregnant women towards management of pregnancy-induced hypertension in southwest Nigeria. J Adv Med Pharm Sci. 2016; 11(2): 1–10. https://doi:10.9734/JAMPS/2016/29764

Ministerio de Salud y Protección Social. Lineamiento técnico y operativo de la ruta integral de atención en salud materno perinatal. Bogotá, Colombia. MinSalud. 2017. 145 p.

Menor RM, Aguilar CM, Mur VN, Santana CM. Efectividad de las intervenciones educativas para la atención de la salud. Revisión sistemática. Medisur. 2017;15(1):71-84.

Aldhafeeri MK, Alahmadi KF, Alalyani AM, Naeem AM, Abotalib RA, Jahaz TA, et al. Impact of health education on knowledge and preventive behaviour for pregnancy related issues in Saudi Arabia : a systematic review. CTBB. 2019;2(1):146–155.

Parsa S, Khajouei R, Baneshi MR, Aali BS. Improving the knowledge of pregnant women using a pre-eclampsia app: A controlled before and after study. Int J Med Inform. 2019; 125: 86–90.

Alnuaimi K, Abuidhail J, Abuzaid H. The effects of an educational programme about preeclampsia on women’s awareness: a randomised control trial. Int Nurs Rev. 2020; 67(4): 1–11.

Jacob LM, Mafetoni RR, Lopes MH, Shimo AK. Knowledge, attitude and practice about hypertensive gestacional syndrome among pregnant women: a randomized clinical trial. Texto e Contexto Enferm. 2022; 31: e20210018.

Vergara O, Pulido G, Montenegro J, González C, Ortiz Y. El lenguaje estandarizado enfermero: conocimiento y perspectiva para el cuidado materno-perinatal. Investig. enferm. imagen desarro. 2017;21(1):1–11.

Alanis M, Perez B, Alvarez M, Rojas M. Autocuidado en la mujer embarazada en una comunidad del estado de México. Repositorio Institucional UAEM. 2015;61–72.

Moher D, Shamseer L, Clarke M, Ghersi D, Liberati A, Petticrew M, et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev. 2015; 4(1).

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 2021;372:n71.

Guyatt G, Oxman AD, Akl EA, Kunz R, Vist G, Brozek J, et al. GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables. J. Clin. Epidemiol. 2011; 64(4), 383–394. https://doi/10.1016/j.jclinepi.2010.04.026

Sanabria AJ, Rigau D, Rotaeche R, Selva A, Marzo-Castillejo M, Alonso-Coello P. Sistema GRADE: metodología para la realización de recomendaciones para la práctica clínica. Aten Primaria. 2015; 47(1): 48-55.

Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, et al. Cochrane Handbook for Systematic Reviews of Interventions. Version 6.2. Cochrane. 2021.

Sterne JA, Hernán MA, Reeves BC, Savovic J, Berkman ND, Viswanathan M, et al. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016; 12: 355–362.

Haerani, Suswani A, Miftahul J. The effect of health education in pregnant mothers against knowledge about preeklampsia. Jurnal Life Birth. 2019; 3(2): 68–76.

Linggardini K, Apriliana HD. Pengaruh pendidikan kesehatan pada ibu hamil terhadap pengetahuan tentang preeklamsia di wilayah kerja puskesmas sokaraja I. Medisains J Ilm Ilmu-ilmu Kesehat. 2016; 14(2):10–5.

El Sayed HAE, Said SA, Mohy HF, Emam AM. Efficacy of an intervention based on theory of planned behavior on self-care management among women with pregnancy induced hypertension. IOSR-JNHS. 2020; 9(1):7–20. https://doi/10.9790/1959-0901030720

Singh N, Ponna SN, Rajeshwari KR. Efficacy of structured teaching programme on home care management of pregnancy induced hypertension in primigravida mothers: a tertiary hospital study. Int J Reprod Contracept Obstet Gynecol. 2017;6(9):3808-3812.



Cómo citar

Ulloa-Sabogal IM, Pérez-Jaimes GA, Arias-Rojas EM, Cañon-Montañez W. Health education interventions on knowledge and self-care practices for hypertensive disorders during pregnancy: systematic review and meta-analysis protocol. Revista Cuidarte [Internet]. 21 de diciembre de 2022 [citado 17 de junio de 2024];14(1). Disponible en:



Los datos de descargas todavía no están disponibles.

Artículos más leídos del mismo autor/a

1 2 > >>