Cardiometabolic factors related to post-COVID-19 conditions: a scoping review

Authors

DOI:

https://doi.org/10.15649/cuidarte.4290

Keywords:

Adult, COVID-19, Syndrome, Cardiometabolic Risk Factors

Abstract

Highlights

  • Post-COVID-19 syndrome is a pathology with several physical and psychosocial consequences.
  • Early identification of cardiometabolic risk factors improves the prevention of complications in the clinical picture.
  • The findings highlight the importance of the health system in preventing SARS-CoV-2 infection from progressing to serious illness.
  • Changes in therapeutic, diagnostic and prognostic standards related to Covid-19 remain a challenge in health care.

Introduction: Post-COVID syndrome is a pathology that involves multiple sequelae. It is important to identify cardiometabolic risk factors as a way of preventing complications.  Objective: To map the scientific evidence related to cardiometabolic factors in long post-COVID-19 conditions. Materials and Methods: Scoping review with the guiding question: What scientific evidence relates cardiometabolic factors to patients with long post-Covid-19 syndrome? The sources of information used were six databases via the CAPES journal portal. For the gray literature, we used the CAPES catalog of theses and dissertations, the Brazilian Digital Library of Theses and Dissertations, the Who Library Database and the medRxiv and OpenGrey repositories. The following descriptors were used: Adult, heart disease risk factors, Syndrome, SARS-CoV-2 and Covid 19 crossed using the Boolean operators AND and OR. Results: 14 studies were included. The cardiometabolic factors found were: abnormal levels of triglycerides, glycated hemoglobin, ferritin, inflammatory processes, decreased platelets, phospholipids and endothelial cells, oxidative stress, higher concentrations of monosaccharides and reduced polysaccharides, increased LDL, ALT, AST and bilirubin, with reduced GFR. Discussion:  Patients with long-term COVID report persistent and debilitating symptoms that affect recovery, quality of life, economic and social activities. In addition to increased resting heart rate, tachycardia, palpitations, hypotension, syncope, orthostatic tachycardia, angina and heart attack. Conclusions:  Cardiometabolic factors expose the vulnerability of individuals affected by long Covid-19, so strategies are needed to reduce the systemic inflammatory impact of the disease and its clinical consequences.

How to cite this article: Cruz Neto, João; Olivindo, Vinícius Fiuza Carlos; Santos, José Arthur Guimarães dos; Silva, Kadson Araujo da; Junior, Romulo de Oliveira Sales. Cardiometabolic factors related to post-COVID-19 conditions: scoping review. Revista Cuidarte. 2025;16(2):e4290.  https://doi.org/10.15649/cuidarte.4920

Author Biographies

  • João Cruz Neto, Universidade Federal do Ceará – UFC. Fortaleza, Ceará, Brazil. 

    Enfermeiro, mestre em enfermagem pela Universidade da Integração Internacional da Lusofonia Afro-Brasileira. 

  • Carlos Vinícius Fiuza Olivindo, Universidade Federal do Ceará – UFC. Fortaleza, Ceará, Brazil.

    Universidade Federal do Ceará – UFC. Fortaleza, Ceará, Brasil.

  • José Arthur Guimarães dos Santos, Universidade Federal da Paraíba - UFPB. João Pessoal, Paraíba, Brazil. 

    Enfermeiro. Mestrando do Programa de Pós-Graduação em Enfermagem (PPGENF/UFPB). Especialista em Atenção Cardiovascular pela modalidade de Residência (HUNE/FACENE). 

  • Kadson Araujo da Silva, Universidade Federal do Ceará – UFC. Fortaleza, Ceará, Brazil.

    Universidade Federal do Ceará – UFC. Fortaleza, Ceará, Brasil.

  • Romulo de Oliveira Sales Junior, Universidade Estadual Paulista - UNESP. São Paulo, Brazil.

    Odontólogo. Mestre em Ciências Odontológicas pela Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP.

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Published

2025-07-24

How to Cite

1.
Cruz Neto J, Olivindo VFC, Santos JAG dos, Silva KA da, Junior R de OS. Cardiometabolic factors related to post-COVID-19 conditions: a scoping review. Revista Cuidarte [Internet]. 2025 Jul. 24 [cited 2026 Apr. 27];16(2). Available from: https://revistas.udes.edu.co/cuidarte/article/view/4290

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