COVID-19: Factors associated with symptoms of anxiety and depression in the ICU

Authors

  • Laura Andrea Díaz-Mayorga Universidad de Santander. Facultad de Ciencias Médicas y de la Salud. Instituto de Investigación Masira, Bucaramanga, Santander, Colombia. https://orcid.org/0009-0000-2800-8520
  • Harol Giovanni Vivas-López Universidad de Santander. Facultad de Ciencias Médicas y de la Salud. Instituto de Investigación Masira, Bucaramanga, Santander, Colombia. https://orcid.org/0009-0005-6273-9032
  • Claudia Consuelo Torres Contreras Universidad de Santander. Facultad de Ciencias Médicas y de la Salud. Instituto de Investigación Masira, Bucaramanga, Santander, Colombia. https://orcid.org/0000-0001-7064-9380
  • Lyda Z. Rojas Fundación Cardiovascular de Colombia, Floridablanca, Santander, Colombia. https://orcid.org/0000-0002-4252-7105
  • Norma C. Serrano Fundación Cardiovascular de Colombia, Floridablanca, Santander, Colombia. https://orcid.org/0000-0003-3532-2002
  • Angie Yarlady Serrano-García Fundación Cardiovascular de Colombia, Floridablanca, Santander, Colombia. https://orcid.org/0000-0002-2583-7144
  • Margarita Rosa Parra Ortiz Universidad Militar Nueva Granada, Bogotá D.C, Colombia. https://orcid.org/0009-0000-0582-6627
  • Doris Cristina Quintero-Lesmes Fundación Cardiovascular de Colombia, Floridablanca, Santander, Colombia. https://orcid.org/0000-0001-8875-0110

DOI:

https://doi.org/10.15649/cuidarte.3998

Keywords:

Anxiety, Depression, Healthcare Personnel, Intensive Care Units, COVID-19

Abstract

Highlights

  • The COVID-19 pandemic posed a challenge to healthcare institutions, especially ICU personnel, exposing them to physical and mental health risks.
  • Healthcare professionals, including nurses and doctors, faced anxiety and depression due to increased workloads and fear of infection.
  • COVID-19 symptoms and working in both general ICUs and COVID-19 ICUs were identified as significant factors contributing to anxiety and depression among healthcare staff.
  • Women in ICU healthcare roles show a slightly higher susceptibility to anxiety and depression symptoms compared to men.

Introduction: The COVID-19 pandemic led to a high prevalence of anxiety and depression among healthcare personnel. Objective: To assess the prevalence and independent risk factors associated with anxiety and depression symptoms among healthcare staff working in Intensive Care Units (ICUs) during the COVID-19 pandemic in Bucaramanga and its metropolitan area. Materials and Methods:   This was an analytical cross-sectional study. Anxiety and depression were measured using the Hopkins Symptom Checklist-25 (HSCL-25). Bivariate and multivariate analyses were conducted using linear regressions to investigate associated factors. Results: A total of 288 people were included in the study. The prevalence of anxiety and depression symptoms was 8.34% (95% CI: 5.41-12.14%). In the bivariate analysis, six factors were associated with depression and anxiety symptoms; however, only three remained in the multivariate analysis: female sex (β=0.085, 95% CI; 0.019 - 0.151), experiencing COVID-19 symptoms in the past 14 days (β= 0.115, 95% CI: 0.024 - 0.205), and having worked in general ICUs and COVID-19 ICUs (β =0.009, 95% CI: 0.025 - 0.173). Discussion: The prevalence of anxiety and depression symptoms was considerably lower than reported in the scientific literature. Conclusions: In the studied population, although the prevalence of depression and anxiety symptoms was low, three independent factors were found to be statistically associated with the presence of these mental symptoms.

How to cite this article: Díaz-Mayorga Laura Andrea, Vivas-López Harol Giovanni, Torres Contreras Claudia Consuelo, Rojas Lyda Z, Serrano Norma C, Serrano-García Angie Yarlady, Parra Ortiz Margarita Rosa, Quintero-Lesmes Doris Cristina. COVID-19: Factors associated with symptoms of anxiety and depression in the ICU. Revista Cuidarte. 2025;16(1):e3998.  https://doi.org/10.15649/cuidarte.3998

Author Biographies

  • Laura Andrea Díaz-Mayorga , Universidad de Santander. Facultad de Ciencias Médicas y de la Salud. Instituto de Investigación Masira, Bucaramanga, Santander, Colombia.

    Universidad de Santander. Facultad de Ciencias Médicas y de la Salud. Instituto de Investigación Masira, Bucaramanga, Santander, Colombia.

  • Harol Giovanni Vivas-López , Universidad de Santander. Facultad de Ciencias Médicas y de la Salud. Instituto de Investigación Masira, Bucaramanga, Santander, Colombia.

    Universidad de Santander. Facultad de Ciencias Médicas y de la Salud. Instituto de Investigación Masira, Bucaramanga, Santander, Colombia.

  • Claudia Consuelo Torres Contreras, Universidad de Santander. Facultad de Ciencias Médicas y de la Salud. Instituto de Investigación Masira, Bucaramanga, Santander, Colombia.

    Universidad de Santander. Facultad de Ciencias Médicas y de la Salud. Instituto de Investigación Masira, Bucaramanga, Santander, Colombia.

  • Lyda Z. Rojas, Fundación Cardiovascular de Colombia, Floridablanca, Santander, Colombia.

    Fundación Cardiovascular de Colombia, Floridablanca, Santander, Colombia.

  • Norma C. Serrano, Fundación Cardiovascular de Colombia, Floridablanca, Santander, Colombia.

    Fundación Cardiovascular de Colombia, Floridablanca, Santander, Colombia.

  • Angie Yarlady Serrano-García, Fundación Cardiovascular de Colombia, Floridablanca, Santander, Colombia.

    Fundación Cardiovascular de Colombia, Floridablanca, Santander, Colombia.

  • Margarita Rosa Parra Ortiz, Universidad Militar Nueva Granada, Bogotá D.C, Colombia.

    Universidad Militar Nueva Granada, Bogotá D.C, Colombia.

  • Doris Cristina Quintero-Lesmes, Fundación Cardiovascular de Colombia, Floridablanca, Santander, Colombia.

    Fundación Cardiovascular de Colombia, Floridablanca, Santander, Colombia.

References

Wu F, Zhao S, Yu B, Chen YM, Wang W, Song ZG, et al. A new coronavirus associated with human respiratory disease in China. Nature. 2020;579(7798):265–9. http://dx.doi.org/10.1038/s41586-020-2008-3

World Health Organization. WHO Director-General’s opening remarks at the media briefing on COVID-19 [Internet] 2020 [Cited: March 07, 2024]. Available from: https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020

Danet Danet A. Impacto psicológico de la COVID-19 en profesionales sanitarios de primera línea en el ámbito occidental. Una revisión sistemática. Med Clínica. 2021;156(9):449–58. http://dx.doi.org/10.1016/j.medcli.2020.11.009

Lai J, Ma S, Wang Y, Cai Z, Hu J, Wei N, et al. Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019. JAMA Netw Open. 2020;3(3):e203976. http://dx.doi.org/10.1001/jamanetworkopen.2020.3976

Wang C, Pan R, Wan X, Tan Y, Xu L, McIntyre RS, et al. A longitudinal study on the mental health of general population during the COVID-19 epidemic in China. Brain Behav Immun. 2020;87:40–8. http://dx.doi.org/10.1016/j.bbi.2020.04.028

Shanafelt T, Ripp J, Trockel M. Understanding and Addressing Sources of Anxiety Among Health Care Professionals During the COVID-19 Pandemic. JAMA. 2020;323(21):2133. http://dx.doi.org/10.1001/jama.2020.5893

Xiang YT, Yang Y, Li W, Zhang L, Zhang Q, Cheung T, et al. Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed. Lancet Psychiatry. 2020;7(3):228–9. https://doi.org/10.1016/S2215-0366(20)30046-8

Salari N, Khazaie H, Hosseinian-Far A, Khaledi-Paveh B, Kazeminia M, Mohammadi M, et al. The prevalence of stress, anxiety and depression within front-line healthcare workers caring for COVID-19 patients: a systematic review and meta-regression. Hum Resour Health. 2020;18(1):100. http://dx.doi.org/10.1186/s12960-020-00544-1

Pappa S, Ntella V, Giannakas T, Giannakoulis VG, Papoutsi E, Katsaounou P. Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: A systematic review and meta-analysis. Brain Behav Immun. 2020;88:901–7.http://dx.doi.org/10.1016/j.bbi.2020.05.026

Colmenares-Mejía C, Quintero-Lesmes DC, Acosta IS, Suárez DP, Meneses L, Sopó Rincón OL, et al. Seroprevalence of SARS-CoV-2 Infection among Vaccinated Health Workers and Hospital Staff. Arch Clin Biomed Res. 2022;06(02):290-295. https://www.fortunejournals.com/articles/seroprevalence-of-sarscov2-infection-among-vaccinated-health-workers-and-hospital-staff.html

Derogatis LR, Lipman RS, Rickels K, Uhlenhuth EH, Covi L. The Hopkins Symptom Checklist (HSCL): A self-report symptom inventory. Behav Sci. 1974;19(1):1–15. http://dx.doi.org/10.1002/bs.3830190102

Clavería A, Rodríguez-Barragán M, Fernández-San-Martín MI, Nabbe P, Le Reste JY, Miguéns-Blanco I, et al. Traducción y adaptación transcultural al español, catalán y gallego de la escala Hopkins Symptom Checklist-25 para la detección de depresión en Atención Primaria. Aten Primaria. 2020;52(8):539–47. http://dx.doi.org/10.1016/j.aprim.2020.05.017

Rodríguez-Barragán M, Fernández-San-Martín MI, Clavería-Fontán A, Aldecoa-Landesa S, Casajuana-Closas M, Llobera J, et al. Validation and Psychometric Properties of the Spanish Version of the Hopkins Symptom Checklist-25 Scale for Depression Detection in Primary Care. Int J Environ Res Public Health. 2021;18(15):7843. http://dx.doi.org/10.3390/ijerph18157843

Díaz-Mayorga LA, Vivas-López HG, Torres Contreras CC, Rojas LZ, Serrano NC, Serrano-García AY, et al. Base Datos COVID-19 - COVID-19: Factors associated with symptoms of anxiety and depression in the ICU. GitLab [Internet] 2024 [Cited: March 06, 2024]. Available from: https://gitlab.com/investigaciones1/Covid-19_UCI

Peng X, Meng X, Li L, Hu C, Liu W, Liu Z, et al. Depressive and Anxiety Symptoms of Healthcare Workers in Intensive Care Unit Under the COVID-19 Epidemic: An Online Cross-Sectional Study in China. Front Public Health. 2021;9:603273. http://dx.doi.org/10.3389/fpubh.2021.603273

Liu Z, Wu J, Shi X, Ma Y, Ma X, Teng Z, et al. Mental Health Status of Healthcare Workers in China for COVID-19 Epidemic. Ann Glob Health. 2020;86(1):128. http://dx.doi.org/10.5334/aogh.3005

Motahedi S, Aghdam NF, Khajeh M, Baha R, Aliyari R, Bagheri H, et al. Anxiety and depression among healthcare workers during COVID-19 pandemic: A cross-sectional study. Heliyon. 2021;7(12):e08570. http://dx.doi.org/10.1016/j.heliyon.2021.e08570

Lasalvia A, Amaddeo F, Porru S, Carta A, Tardivo S, Bovo C, et al. Levels of burn-out among healthcare workers during the COVID-19 pandemic and their associated factors: a cross-sectional study in a tertiary hospital of a highly burdened area of north-east Italy. BMJ Open. 2021;11(1):e045127. http://dx.doi.org/10.1136/bmjopen-2020-045127

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Published

2025-03-26

How to Cite

1.
Díaz-Mayorga LA, Vivas-López HG, Torres Contreras CC, Rojas LZ, Serrano NC, Serrano-García AY, et al. COVID-19: Factors associated with symptoms of anxiety and depression in the ICU. Revista Cuidarte [Internet]. 2025 Mar. 26 [cited 2025 Apr. 6];16(1). Available from: https://revistas.udes.edu.co/cuidarte/article/view/3998

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