Two epidemics, one patient: coinfection by SARS-CoV-2 and influenza in Colombia

Authors

  • Jhon H. Quintana-Ospina Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia. https://orcid.org/0009-0008-4848-7635
    • Luis M. Osorio-Toro Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia. https://orcid.org/0000-0002-1971-6354
      • Gustavo A. Urriago-Osorio Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia. https://orcid.org/0000-0002-4627-7908
        • Jasbleidy Posu-Barco Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia. https://orcid.org/0009-0006-4448-2269
          • Giovanna P. Rivas-Tafurt Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia. https://orcid.org/0000-0002-9709-6656
            • Jorge E. Daza-Arana Physiotherapy Program, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. https://orcid.org/0000-0002-4936-1507
              • José M. Oñate-Gutiérrez Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia. https://orcid.org/0000-0002-6180-792X

                DOI:

                https://doi.org/10.15649/cuidarte.4264

                Keywords:

                COVID-19, Influenza, Coinfection, Aortic Valve Insufficiency, Cardiac Prosthesis Implantation, Mortality

                Abstract

                Highlights

                • Coinfection with SARS-CoV-2 and the influenza virus (Flurona) is uncommon.
                • Diagnosis is complex due to the similarity in the clinical manifestations of both diseases; therefore, microbiological and imaging tests play a fundamental role.
                • Treatment represents a challenge, as the use of oseltamivir and dexamethasone in these patients remains controversial.
                • A multidisciplinary approach to patients with Flurona is imperative to optimize clinical outcomes.

                Introduction: Coinfection by SARS-CoV-2 and influenza (commonly referred to as "Flurona") presents a significant diagnostic and therapeutic challenge in pandemic and postpandemic settings. Although the two viruses share clinical similarities and transmission routes, their treatments differ substantially. The early suspicion of viral coinfection is crucial, particularly in patients with comorbidities or atypical clinical courses. A literature review was conducted in PubMed, Scopus, and Google Scholar (Spanish and English), identifying few documented clinical reports in Colombia. Case Description: We report the case of an 83-year-old male patient with a significant cardiovascular history, admitted to the intensive care unit for congestive heart failure and severe aortic valve disease. During hospitalization, the patient developed respiratory failure, and coinfection with influenza and SARS-CoV-2 was confirmed. Treatment included oseltamivir, oxygen therapy, and therapeutic thoracentesis. Transcatheter aortic valve implantation was indicated, but the patient died during the procedure. Conclusion: Coinfection by SARS-CoV-2 and influenza should be considered in the differential diagnosis of patients with acute respiratory distress, particularly in contexts of concurrent viral circulation. Prompt recognition enables targeted therapeutic intervention. A multidisciplinary approach is essential to optimize the prognosis in patients with complex comorbidities.

                How to cite this article: Quintana-Ospina Jhon H, Osorio-Toro Luis M, Urriago-Osorio Gustavo A, Posu-Barco Jasbleidy, Rivas-Tafurt Giovanna P, Daza-Arana Jorge E, Oñate-Gutiérrez José M. Two epidemics, one patient: coinfection by SARS-CoV-2 and influenza in Colombia. Revista Cuidarte. 2025;16(3):e4264.  https://doi.org/10.15649/cuidarte.4264

                Author Biographies

                • Jhon H. Quintana-Ospina, Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia.

                  Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia.

                • Luis M. Osorio-Toro, Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia.

                  Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia.

                • Gustavo A. Urriago-Osorio, Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia.

                  Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia.

                • Jasbleidy Posu-Barco, Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia.

                  Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia.

                • Giovanna P. Rivas-Tafurt, Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia.

                  Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia.

                • Jorge E. Daza-Arana, Physiotherapy Program, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia.

                  Physiotherapy Program, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia.

                • José M. Oñate-Gutiérrez, Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia.

                  Specialization in Internal Medicine, Faculty of Health, Universidad Santiago de Cali, Cali, Colombia. Clínica de Occidente Research and Education Group (GIECDO), Clínica de Occidente S.A., Cali, Colombia.

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                Published

                2025-12-17

                How to Cite

                1.
                Quintana-Ospina JH, Osorio-Toro LM, Urriago-Osorio GA, Posu-Barco J, Rivas-Tafurt GP, Daza-Arana JE, et al. Two epidemics, one patient: coinfection by SARS-CoV-2 and influenza in Colombia. Revista Cuidarte [Internet]. 2025 Dec. 17 [cited 2026 May 13];16(3). Available from: https://revistas.udes.edu.co/cuidarte/article/view/4264

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