Hypertension and risk factors in Peruvian outpatients

Authors

  • Lizbeth Cieza Najarro Registered Nurse. Universidad Nacional Autónoma de Chota. Cajamarca, Peru. 
    • Conceptualization
    • Data Curation
    • Formal Analysis
    • Investigation
    • Methodology
    • Project Administration
    • Resources
    • Validation
    • Visualization
    • Writing – Original Draft Preparation
    • Writing – Review & Editing
  • Carmencita Muñoz Estela Registered Nurse. Universidad Nacional Autónoma de Chota. Cajamarca, Peru. 
    • Conceptualization
    • Data Curation
    • Formal Analysis
    • Investigation
    • Methodology
    • Project Administration
    • Resources
    • Validation
    • Visualization
    • Writing – Original Draft Preparation
    • Writing – Review & Editing
  • José Ander Asenjo-Alarcón PhD in Health Sciences, Epidemiologist. Faculty of Health Sciences, Universidad Nacional Autónoma de Chota. Cajamarca, Peru.
    • Conceptualization
    • Data Curation
    • Formal Analysis
    • Investigation
    • Methodology
    • Project Administration
    • Resources
    • Validation
    • Visualization
    • Writing – Original Draft Preparation
    • Writing – Review & Editing

DOI:

https://doi.org/10.15649/cuidarte.5177

Keywords:

Chronic Disease, Hypertension, Risk Factors, Health Centers, Primary Health Care, Peru

Abstract

Highlights

  • Hypertension has a long latency period; therefore, continuous assessment of risk factors may help prevent its onset.
  • Population-level risk factors are amenable to modification or control through effective health education and awareness strategies.
  • Identifying risk factors according to their potential impact enables more targeted, evidence-informed actions, thereby improving outcomes.
  • Preventive and health promotion measures have demonstrated favorable results in chronic diseases such as hypertension and should always be recommended.

Introduction: Hypertension has multiple risk factors that need to be identified in specific contexts to guide the prioritization and implementation of effective control strategies.  Objective: To assess the association between hypertension and risk factors in Peruvian outpatients. Materials and Methods: An analytical, retrospective, observational study was conducted in 286 patients attending a primary healthcare center. High blood pressure and risk factor values were obtained using two diagnostic interpretation guides adapted by official institutions. Univariate analysis was performed using frequency distributions, and associations were assessed with the chi-square test for homogeneity (p<0.05) and prevalence odds ratios. Results: total of 37.76% of patients had hypertension. The most frequent risk factors were low HDL cholesterol (56.29%) and elevated body mass index (60.49%). Elevated HbA1c was associated with a more than threefold increased risk of hypertension. Elevated total cholesterol, LDL cholesterol, and fasting blood glucose were associated with a more than twofold increased risk in women. In men, increased waist circumference was associated with a more than threefold increased risk, and in older adults, with a more than twofold increased risk. Discussion:  Context shapes the association between hypertension and risk factors, given the specific characteristics of each setting and differing social determinants. Conclusion: Hypertension was significantly associated with elevated HbA1c, total cholesterol, LDL cholesterol, fasting blood glucose, and waist circumference. Timely and appropriate interventions targeting the identified risk factors could slow the occurrence of hypertension.

How to cite this article: Cieza Najarro Lizbeth, Muñoz Estela Carmencita, Asenjo-Alarcón José Ander. Hypertension and risk factors in Peruvian outpatients. Revista Cuidarte. 2026;17(2):e5177. https://doi.org/10.15649/cuidarte.5177

Author Biographies

  • Lizbeth Cieza Najarro, Registered Nurse. Universidad Nacional Autónoma de Chota. Cajamarca, Peru. 

    Registered Nurse. Universidad Nacional Autónoma de Chota. Cajamarca, Peru. 

  • Carmencita Muñoz Estela, Registered Nurse. Universidad Nacional Autónoma de Chota. Cajamarca, Peru. 

    Registered Nurse. Universidad Nacional Autónoma de Chota. Cajamarca, Peru. 

  • José Ander Asenjo-Alarcón, PhD in Health Sciences, Epidemiologist. Faculty of Health Sciences, Universidad Nacional Autónoma de Chota. Cajamarca, Peru.

    PhD in Health Sciences, Epidemiologist. Faculty of Health Sciences, Universidad Nacional Autónoma de Chota. Cajamarca, Peru.

References

Götzinger F, Kunz M, Lauder L, Böhm M, Mahfoud F. Arterial hypertension - clinical trials update 2022. Hypertens Res. 2022;45:1140-1146. https://doi.org/10.1038/s41440-022-00931-2

Hengel FE, Sommer C, Wenzel U. Arterielle Hypertonie – Eine Übersicht für den ärztlichen Alltag. Dtsch Med Wochenschr. 2022;147(7):414-428. https://doi.org/10.1055/a-1577-8663

Peng W, Li K, Yan AF, Shi Z, Zhang J, Cheskin LJ, et al. Prevalence, Management, and Associated Factors of Obesity, Hypertension, and Diabetes in Tibetan Population Compared with China Overall. Int J Environ Res Public Health. 2022;19(14):8787 https://doi.org/10.3390/ijerph19148787

Yang G, Qian T, Sun H, Xu Q, Hou X, Hu W, et al. Adjustment for body mass index changes inverse associations of HDL-cholesterol with blood pressure and hypertension to positive associations. J Hum Hypertens. 2022;36:570-579. https://doi.org/10.1038/s41371-021-00548-x

Deng G, Li Y, Cheng W. Association of Lipid Levels With the Prevalence of Hypertension in Chinese Women: A Cross-Sectional Study Based on 32 Health Check Centers. Front Endocrinol. 2022;13:904237. https://doi.org/10.3389/fendo.2022.904237

Omar SM, Musa IR, Abdelbagi O, Sharif ME, Adam I. The association between glycosylated haemoglobin and newly diagnosed hypertension in a non-diabetic Sudanese population: a cross-sectional study. BMC Cardiovasc Disord. 2022;22:208. https://doi.org/10.1186/s12872-022-02649-y

Przezak A, Bielka W, Pawlik A.Hypertension and Type 2 Diabetes-The Novel Treatment Possibilities. Int J Mol Sci. 2022;23(12):6500. https://doi.org/10.3390/ijms23126500

Wang Q, Song X, Du S, Du W, Su C, Zhang J, et al. Waist Circumference Trajectories in Relation to Blood Pressure and the Risk of Hypertension in Chinese Adults. Nutrients. 2022;14(24):5260. https://doi.org/10.3390/nu14245260

El Meouchy P, Wahoud M, Allam S, Chedid R, Karam W, Karam S. Hypertension Related to Obesity: Pathogenesis, Characteristics and Factors for Control. Int J Mol Sci. 2022;23(20):12305. https://doi.org/10.3390/ijms232012305

Shams E, Kamalumpundi V, Peterson J, Gismondi RA, Oigman W, de Gusmão Correia ML. Highlights of mechanisms and treatment of obesity-related hypertension. Journal of Human Hypertension. 2022;36:785-793. https://doi.org/10.1038/s41371-021-00644-y

American Heart Association. High Blood Pressure. [Internet] 2021 [cited 2025 Jan 5]. Available from: https://www.heart.org/en/health-topics/high-blood-pressure

Ministerio de Salud del Perú. Guía Técnica: Guía de Práctica Clínica para el Diagnóstico, Tratamiento y Control de la Enfermedad Hipertensiva, Resolución Ministerial N.° 031-2015-MINSA. MINSA. 2015. Consulta: Enero 5, 2025. Disponible en: https://www.gob. pe/institucion/minsa/normas-legales/195692-031-2015-minsa

Cieza Najarro L, Muñoz Estela C, Asenjo-Alarcón JA. Matriz Hipertensión y factores de riesgo. Mendeley Data.2025. https://doi.org/10.17632/kzt522p2ht.1

Moussouni A, Sidi-Yakhlef A, Hamdaoui H, Aouar A, Belkhatir D. Prevalence and risk factors of prehypertension and hypertension in Algeria. BMC Public Health. 2022;22:1571. https://doi.org/10.1186/s12889-022-13942-y

Zhao Y, Yang X, Wu Y, Huang H, Hu F, Zhang M, et al. Association of triglyceride-glucose index and its 6-year change with risk of hypertension: A prospective cohort study. Nutr Metab Cardiovasc Dis. 2023;33(3):568-76. https://doi.org/10.1016/j.numecd.2022.12.001

Gerdts E, Sudano I, Brouwers S, Borghi C, Bruno RM, Ceconi C, et al. Sex differences in arterial hypertension: A scientific statement from the ESC Council on Hypertension, the European Association of Preventive Cardiology, Association of Cardiovascular Nursing and Allied Professions, the ESC Council for Cardiology Practice, and the ESC Working Group on Cardiovascular Pharmacotherapy. Eur Heart J. 2022;43(46):4777-4788. https://doi.org/10.1093/eurheartj/ehac470

Gorostidi M, Gijón-Conde T, de la Sierra A, Rodilla E, Rubio E, Vinyoles E, et al. Practice guidelines for the management of arterial hypertension of the Spanish Society of Hypertension. Hipertens Riesgo Vasc. 2022;39(4):174-194. https://doi.org/10.1016/j. hipert.2022.09.002

Lin YH, Liu YH, Wu DW, Su HM, Chen SC. Dyslipidemia Increases the Risk of Incident Hypertension in a Large Taiwanese Population Follow-Up Study. Nutrients. 2022;14(16):3277. https://doi.org/10.3390/nu14163277

Wu H, Yu Z, Huang Q. Characteristics of serum lipid levels in patients with hypertension: a hospital-based retrospective descriptive study. BMJ Open. 2022;12(6):e054682. https://doi. org/10.1136/bmjopen-2021-054682

Sun J, Wang X, Terry PD, Ren X, Hui Z, Lei S, et al. Interaction effect between overweight/ obesity and alcohol consumption on hypertension risk in China: a longitudinal study. BMJ Open. 022;12(7):e061261. https://doi.org/10.1136/bmjopen-2022-061261

Ali N, Mohanto NC, Nurunnabi SM, Haque T, Islam F. Prevalence and risk factors of general and abdominal obesity and hypertension in rural and urban residents in Bangladesh: a cross-sectional study. BMC Public Health. 2022;22:1707. https://doi.org/10.1186/s12889- 022-14087-8

Melichova J, Sivco P, Rusnak M, Phuong Truc P, Majdan M. International evidence-based guidelines on hypertension and type 2 diabetes mellitus: A systematic review. J Public Health Res. 2023;12. https://doi.org/10.1177/22799036221146913

Asenjo-Alarcón JA. Oblitas Gonzales A. Complicaciones crónicas microvasculares en usuarios con diabetes mellitus tipo 2 de una ciudad andina del Perú. Rev. salud pública. 2022;24(3):1-8. https://doi.org/10.15446/rsap.v24n3.100418

Asenjo-Alarcón JA, Hernández Fiestas RW. Usuarios de un programa de ejercicio físico y el riesgo de prediabetes. Av. enferm. 2021;39(2):207-214. https://doi.org/10.15446/ av.enferm.v39n2.92307

Xu L, Wen X, Yang Y, Cui D. Trends and Comparisons of Blood Pressure and Fasting Plasma Glucose in Patients with Hypertension, Diabetes, and Comorbidity: 4-Year Follow-Up Data. Risk Manag Healthc Policy. 2022;15:2221-2232. https://doi.org/10.2147/RMHP.S385815

Silva BV, Sousa C, Caldeira D, Abreu A, Pinto FJ. Management of arterial hypertension: Challenges and opportunities. Clin Cardiol. 2022;45(11):1094-1099. https://doi.org/10.1002/clc.23938

Reynolds AN, Akerman A, Kumar S, Diep Pham HT, Coffey S, Mann J. Dietary fibre in hypertension and cardiovascular disease management: systematic review and meta-analyses. BMC Med. 2022;20(1):139. https://doi.org/10.1186/s12916-022-02328-x

Israfil I, Kusnanto K, Yusuf A, Efendi F. The effect of health education intervention through mobile phone on hypertension patients: A systematic review. Med J Malaysia. 2022;77(2):232-236. PMID: 35338632. https://pubmed.ncbi.nlm.nih.gov/35338632/

Published

2026-06-12

How to Cite

1.
Cieza Najarro L, Muñoz Estela C, Asenjo-Alarcón JA. Hypertension and risk factors in Peruvian outpatients. Revista Cuidarte [Internet]. 2026 Jun. 12 [cited 2026 Jun. 12];17(2). Available from: https://revistas.udes.edu.co/cuidarte/article/view/5177

Downloads

Download data is not yet available.

Similar Articles

1-10 of 678

You may also start an advanced similarity search for this article.